Physical forces play a fundamental role in shaping the behavior and organization of living systems, from individual cells to tissues. Inspired by soft matter physics, we develop quantitative tools and experimental approaches to understand how cells sense, generate, and respond to mechanical cues, and how these interactions shape collective behavior and tissue dynamics.
Our research focuses on the physical principles governing tissue organization, morphogenesis, and collective cell behavior. We are particularly interested in how mechanical forces interact with biochemical signaling to coordinate cellular activities across scales, allowing tissues to self-organize, adapt, and develop robust structures and functions.
To address these questions, we combine approaches from physics, engineering, and cell biology across a range of experimental systems. In particular, embryonic development provides a powerful framework for investigating how tissues acquire shape and organization through the interplay between mechanics and signaling.
Our group is part of the Dynamic Control of Signaling and Gene Expression team at the Institut Curie in Paris, within the Physics of Cells and Cancer Laboratory (formerly Physico-Chimie Curie).
Address:
Institut Curie
Physique des Cellules et Cancer, PCC, UMR168
11, rue Pierre et Marie Curie 75005 Paris France
Phone: ++33 (0)1 56246945
email: karine.guevorkian – at – curie.fr
